The Influence of Solid Microneedles on the Transdermal Delivery of Selected Antiepileptic Drugs
نویسندگان
چکیده
منابع مشابه
The Influence of Solid Microneedles on the Transdermal Delivery of Selected Antiepileptic Drugs
The aim of this project was to examine the effect of microneedle rollers on the percutaneous penetration of tiagabine hydrochloride and carbamazepine across porcine skin in vitro. Liquid chromatography-mass spectrometric analysis was carried out using an Agilent 1200 Series HPLC system coupled to an Agilent G1969A TOF-MS system. Transdermal flux values of the drugs were determined from the stea...
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A review of the microneedles for transdermal drug delivery
Microneedles consist of micron-sized projections similar to needles. They are capable of piercing through the stratum corneum and increase the permeation of active ingredients. Besides active pharmaceutical ingredients, microneedles can also deliver cosmetic agents, biotherapeutics like insulin and vaccines and also are used in diagnostic purposes. This article examines the types of microneedle...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2016
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics8040033